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TOEFL BNC: 7720 COCA: 8411

extreme unhappiness caused by physical or mental suffering(肉体或精神上的)极度痛苦,剧痛,悲痛

His anguish at the outcome of the court case was very clear.得知案子的庭审结果,他痛苦欲绝,这是显而易见的。
In her anguish she forgot to leave a message.万分悲痛之中,她忘了留个口信。

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