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- horned 12
- zonal 1
- interview 1138
- Setting 183
- disneyland 101
- misapply 14
- xylophone 1
- snowy 317
- preparation 1064
- zeta 1
- throw 333
- Together 38
- apply 356
- convenient 654
- mews 17
- Bronze 36
- pressure 1682
- Commitment 288
- jackknife 13
- zindabad 1
- acclaim 261
- overnight 1610
- yep 1
- road rage 34
- zappy 1
- chevron 78
- megabucks 9
- knit 237
- feel like 221
- wrapping 1
- fly-drive 89
- oriental 1611
- provision 714
- zombie 1
- Resemble 330
- place 341
- nymph 12
- evacuate 1451
- xi 1
- well known 705
- death 414
- hetero 82
- brew up 28
- satisfy 301
- Banter 17
- gummy 83
- Desert 173
- no-no 1
- setting 359
- unstable 1656
- excess 350
- feel for sb 75
- Cheap 137
- passer-by 10
- donkey 510
- ymmv 1
- governor 1168
- indeterminate 19
- go off the rails 52
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- publicist 157
- really 172
- airport 105
- tempt 317
- minority 1369
- crotch 63
- mammalian 16
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- Rewarding 77
- yonks 1
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- entertain 1286
- yebo 1
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- zit 1
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- Depend 271
- Suitcase 276
- funfair 70
- living room 182
- trip 286
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- chauvinist 277
- Squeeze 178
- chastisement 87
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- yaar 1
- mica 18
- margarine 12
- release 510
- wrest 1
- generator 1480
- zippered 3
- corporation 730
- get back 76
- recognition 749
- underspent 1
- beating 305
- Plainly 33
- floppy disk 104
- hailstorm 94
- clear out 158
- friendless 132
- exoticism 173
- zoroastrianism 1
- file-sharing 93
- Tell apart 30
- nexus 9
- zealotry 3
- yore 5
- lucky 368
- mechanical 376
- leprous 6
- westernmost 1
- earthenware 220
- kohl 106
- deceptively 99
- Desire 852
- trucking 1
- entire 386
- mastery 66
- Fool 153
- garden flat 83
- wassup 6
- Contestant 165
- Life-saving 35
- applicant 1037
- help yourself 94
- boozy 120
- micronesia 6
- velodrome 1
- face off 57
- hodgepodge 13
- unnecessary 1863
- trollop 1
- yolo 4
- years 4
- seaman 267
- yippee 8
- zapper 4
- yearling 6
- Launch 122
- metadata 10
- clothespin 115
- insanely 169
- circumstance 829
- lane 464
- quarterly 1175
- traitor 367
- zooplankton 1
- hacktivist 169
- microfilm 16
- Thrill 97
- zookeeper 1
- carrel 52
- discovery 1083
- moral 345
- zettabyte 1
- tense 662
- Ministry 292
- manly 368
- Suite 172
- matron 106
- Computer and video games and games played on machines 1
- Crew 212
- discuss 146
- enjoyment 303
- Nauru 6
- outpost 106
- needless 1509
- Shorten 208
- canopy 73
- darkness 405
- maintain 968
- birdlike 184
- merchantable 61
- perinatal 183
- bimonthly 271
- swap meet 140
- elasticated 159
- zambia 1
- work ethic 63
- paper clip 6
- chalk sth up to experience 26
- triumphant 315
- zipper 1
- right on 90
- numb 165
- zapotec 1
- deputy 378
- subsidization 56
- boggy 74
- supply and demand 123
- zionist 1
- oversubscribed 388
- Plot 197
- Exit 263
- zeal 522
- lampoon 10
- yurt 1
- actress 483
- represent 2451
- a sea of something 42
- significantly 425
- Shelter 451
- inauguration 210
- beat down 305
- unsatisfying 658
- yeomanry 5
- metropolis 8
- yuletide 2
- SQUARE 45
- footing 51
- disfigure 329
- yuck 2
- Communicating by radio 7
- unused 6
- promise 452
- wrestler 4
- Alt (key) 16
- romantic 1058
- gremlin 101
- restore 663
- zaikai 1
- hesitation 307
- come down to 78
- sponge 576
- Detonate 31
- scathing 54
- yucca 4
- asylum seeker 126
- flippant 175
- unapproachable 18
- belong 453
- over-age 7
- unedifying 6
- wreathe 5
- anthology 200
- washstand 6
- bookbinder 102
- minus 321
- tour 396
- yachting 1
- up- 16
- choral 97
- belly flop 155
- yous 3
- troth 6
- fijian 47
- yack 8
- wretch 2
- yiddish 1
- deliberately 557
- Miscellaneous games 1
- virology 2
- victor 4
- yemen 6
- nudism 10
- torture 334
- Pervert 89
- x 1
- knotted 11
- Diminutive 355
- windward 7
- optimise 329
- yew 4
- metabolic 9
- hardly 314
- gross 329
- study 496
- disappoint 1652
- churn out 49
- wrung 1
- Indigenous 930
- wellington 5
- blistering 115
- yakka 5
- tajine 8
- acceptable 529
- stare 377
- xenon 1
- canton 67
- precocious 65
- clerical 145
- antiviral 12
- wintry 5
- Innovation 480
- baboon 78
- yomp 1
- scheme 428
- Drawing 39
- weeknight 5
- IMMINENT 45
- xe 1
- bother 273
- devoutly 281
- adult 547
- Science fiction thesaurus 1
- long-sighted 8
- Gruelling 35
- zillion 1
- mistrust 14
- checkmark 61
- BroAden 119
- wept 6
- alter 403
- voile 7
- Suggest 200
- grumpy 94
- sting 641
- courseware 70
- cornice 94
- Types of publishing 1
- Sinew 16
- hit 576
- Diet 219
- guadeloupe 105
- evident 551
- Concierge 116
- pantyhose 15
- aware 347
- temptingly 45
- carnal 100
- half-life 141
- pepperoni 7
- superfluity 59
- supplement 1035
- Relating to the business of publishing 1
- onto 487
- while 413
- SHIFT 165
- razor 296
- safely 353
- office 167
- entrepreneurship 87
- Reimburse 16
- zeitgeist 1
- blackleg 112
- offal 8
- dormitory 544
- exercise 837
- highlighter 11
- postnuptial 30
- tan 344
- workmate 4
- wherefores 5
- scammer 46
- yoof 6
- incontinence 13
- Prosperity 221
- evocation 105
- encounter 697
- sprinkle 716
- Invention 151
- unhealthy 7
- upshot 4
- soul 648
- undulate 7
- frighten sb into sth 64
- titrate 9
- strengthen 577
- aircraft 597
- divide 673
- yolk 4
- wap 8
- pansexual 11
- Lockdown 267
- outreach 514
- yank 6
- Interstate 340
- yeshiva 3
- walkover 6
- articulate 497
- joypad 20
- luck 346
- megahertz 10
- whatsit 6
- expiate 84
- tribespeople 8
- Merry Christmas 49
- yaw 7
- mesmerizing 11
- tic 9
- Institution 200
- benefit 521
- korean 11
- retrieve 909
- modus operandi 13
- welshman 6
- tiring 8
- vitals 7
- housing project 134
- picker 98
- minibus 6
- cortex 52
- acorn 50
- hooey 17
- iron-grey 19
- inbreeding 15
- Intuitive 18
- wetware 5
- xenotransplant 4
- towelling 7
- Ubiquitous 337
- amount to 95
- yokel 3
- whitish 7
- Fluctuate 57
- body stocking 132
- sole 348
- Competitor 498
- curvaceous 85
- Averagely 46
- brouhaha 87
- yobbo 3
- caucasian 95
- sewer 172
- fill out 201
- whitey 5
- Retired 28
- tailor 402
- workaday 6
- weaponize 4
- correspondent 1102
- ytterbium 8
- experience 2598
- waitlist 5
- changeable 315
- catch up 190
- concordance 270
- Legislation 879
- work out 270
- movement 1051
- Effective 867
- teammate 35
- stress 1334
- yule 4
- supernatural 1202
- untypically 6
- yob 4
- zaftig 5
- orient 331
- warmongering 5
- horticulture 123
- ventilator 8
- initiation 223
- wormhole 5
- younger 5
- yah 4
- tonsil 8
- destitute 586
- itinerary 1204
- OS 14
- clandestine 351
- defensible 684
- villein 8
- viscosity 7
- marketer 152
- half-sister 166
- veggie 4
- weightlifter 6
- Darkness 150
- wallflower 6
- upspeak 7
- mouth 113
- guidance 1513
- recently 1447
- clone 105
- wt 6
- audience 1402
- wrt 6
- Polymath 15
- Disabled 163
- sustenance 1468
- demagogue 300
- yammer 6
- chainsaw 226
- Deceive 408
- garbage disposal 56
- mutter 391
- fence off 64
- survey 531
- wrangling 6
- friendship 168
- coalition 354
- unstoppable 8
- participate 808
- unbearable 1308
B2 an important discovery or event that helps to improve a situation or provide an answer to a problem重大进展；突破
Scientists are hoping for a breakthrough in the search for a cure for cancer.科学家们希望在治愈癌症的研究上取得突破。
A major breakthrough in negotiations has been achieved.谈判有了重大进展。
More examples
This drug has been heralded as a major breakthrough in the fight against breast cancer.
They had minor breakthroughs but real success eluded them.
Biological research has often been a precursor to medical breakthroughs which benefit patients.
The leaders emphasized that a substantial breakthrough had been achieved, but there was more work to be done.
Researchers reported another important breakthrough in cancer research.
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