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BNC: 686 COCA: 742

B1 without taking any notice of or being influenced by; not prevented by不管;尽管;无论

I still enjoyed the week despite the weather.尽管天气不好,这一周我过得还是很愉快的。
Despite repeated assurances that the product is safe, many people have stopped buying it.尽管已反复保证了该产品的安全性,很多人还是不再购买。
[ + -ing verb ] He managed to eat a big lunch despite having eaten an enormous breakfast.尽管早餐吃了很多,他午饭还是大吃了一顿。
despite yourself

If you do something despite yourself, you do it although you do not want to or although you know you should not.不由自主地,忍不住地

He laughed despite himself.他忍不住笑了起来。
She took the money from her mother's purse, despite herself.她忍不住从母亲的钱包里拿了钱。

More examples

Trains are still running, despite the snow.

The pop festival passed off peacefully, despite the fears of local residents.

The overall situation is good, despite a few minor problems.

He was able to lead a normal life, despite the illness.

She manages to stay cheerful despite everything.

BNC: 686 COCA: 742
BNC: 686 COCA: 742
BNC: 686 COCA: 742
despite
Despite something: despite, in spite of something, nevertheless...

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