B1 without hope没希望的
B2 completely without skill at a particular activity非常不擅长的
More examples
When he first went for treatment at the hospital he seemed to be a hopeless case.
The characters in his novels inhabit a bleak and hopeless universe.
"It's hopeless, " he said, shaking his head despondently.
The situation seems to become more hopeless with every passing day.
There is no way out of here. We've tried everything - it's hopeless.
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