Our new managing director has reorganized the company a little bit, but nothing has fundamentally changed/altered(= its basic character has not changed).我们的新总裁对公司进行了一些重组,但没有什么根本性的变化。
I still believe that people are fundamentally good.我仍然认为人性本善。
I disagree fundamentally with what you're saying.我完全不同意你所说的。
More examples
She thinks that people are fundamentally good.
Surely his argument is fundamentally true, even if you quibble with the details?