C1 a fault or problem in something or someone that spoils that thing or person or causes it, him, or her not to work correctly缺点;缺陷;瑕疵
a physical condition in which something is wrong with a part of someone's body生理缺陷;生理障碍
to leave a country, political party, etc., especially in order to join an opposing one(尤指为加入敌对国家、政党等)脱离,退出,叛逃
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