B2 [ C usually singular ] what happens to a particular person or thing, especially something final or negative, such as death or defeat命中注定的事;命运;(尤指)厄运
B2 [ U ] a power that some people believe causes and controls all events, so that you cannot change or control the way things will happen天意;定数
More examples
But for a cruel twist of fate, he could now be running his own business.
He showed a stoic resignation towards his fate.
It is somehow fixed in my mind that my fate and that woman's are intertwined.
By an odd quirk of fate, we ended up on the same train.
The fates of both countries seem somehow entwined.
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